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UGO BASILE 47200 Instruction Manual
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UGO BASILE 47200 Instruction Manual

Gsm grip strength meter
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instruction manual
GSM Grip Strength Meter
Cat. No. 47200
UGO BASILE S.R.L.
sales@ugobasile.com / service@ugobasile.com www.
.com
ugobasile

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  • Page 1 GSM Grip Strength Meter Cat. No. 47200 UGO BASILE S.R.L. sales@ugobasile.com / service@ugobasile.com www. .com ugobasile...
  • Page 2 THE INSTRUMENT IN SAFE CONDITIONS. SERVICE AND ADJUSTMENTS SHOULD BE CARRIED OUT BY QUALIFIED PERSON- NEL, AUTHORIZED BY UGO BASILE ORGANIZATION. ANY ADJUSTMENT, MAINTENANCE AND REPAIR OF THE OPENED INSTRUMENT UN- DER VOLTAGE SHOULD BE AVOIDED AS MUCH AS POSSIBLE AND, WHEN INEVITA- BLE, SHOULD BE CARRIED OUT BY A SKILLED PERSON WHO IS AWARE OF THE HAZARD INVOLVED.
  • Page 3 (via the optional grid) in rats and mice. The Grip Strength test is a perfect complement to the gold standard Ugo Basile Rota-Rod de- vice for motor coordination and motor fun- ction experiments. The effects of drugs, toxins, muscle relaxants, disease, ageing or neural damage on muscle strength may be assessed.
  • Page 4 CHECK-LIST Cat. No. 47200 Grip Strength Meter CLIENTE / CUSTOMER______________________________________________ Ordine No. / Order No. ____________________ Data / Date____/_____/______ UB code  CAT.No. Q.ty DESCRIPTION DESCRIZIONE 47200-001 ELECTRONIC UNIT UNITA’ ELETTRONICA 47200-002 TRANSDUCER TRASDUTTORE 47200-004 BLACK PVC BASE W/13mm UPRIGHT BASE PVC NERO CON STATIVO 13mm...

  • Page 5: Table Of Contents

    Page i 47200 Instruction Manual (Rev. 1) C O N T E N T S GENERAL ......................1 ..................1 RINCIPLE OF PERATION 1.1.1 ONSISTENT ESULTS INSTRUMENT DESCRIPTION ................2 ....................3 LECTRONIC 2.1.1 UTOZERO UNCTION & F ........... 4...
  • Page 6 Page ii 47200 Instruction Manual (Rev. 1) ................18 PDATING THE FIRMWARE USING THE PC SOFTWARE PROVIDED WITH GSM ........18 GSM PC S ..............18 OTE ON THE OFTWARE DCA S ................19 TARTING THE OFTWARE ................20 TARTING THE XPERIMENT 6.3.1...

  • Page 7: General

    Grip Strength Meter Cat. 4 7 2 0 0 GENERAL The 47200 Grip Strength Meter (GSM) measures forelimb grip-strength in rats and mouse. The effects of drugs, toxins, muscle relaxants, disease, ageing or neural damage on muscle strength may be assessed.

  • Page 8: Consistent Results

    Page 2 47200 Instruction Manual (Rev. 1) 1.1.1 Consistent Results The GSM device has been designed to make sensitivity experiments easy and con- sistent, thanks to its:  Effective peak detector, for a reliable and automated detection of the animal response ...

  • Page 9: Electronic Unit

    Page 3 47200 Instruction Manual (Rev. 1) Beside the above listen items, the case contains the following items:  External foot pedal  USB Cable  Power Adapter  GSM Software (on USB flash drive)  Operation Manual (on USB flash drive)

  • Page 10: Autozero Function

    Page 4 47200 Instruction Manual (Rev. 1) 2.1.1 Autozero Function When GSM is switched ON, the initial menu choice is between making measurements and configuring the instrument to suit the user’s specific requirements. The detailed menu options will be discussed later.

  • Page 11: Grasping Grids

    Measuring the hind limbs with the standard T-bar or trapeze attachment pieces that come with the machine, is hardly feasible; the grid 47200-325 is useful also in this case. An alternative model has been recently developed, 47200-326, which a “blind”...

  • Page 12: Notes On The Instruction Manual

    USB port. The GSM will be automatically recognized and the drivers will install automatically, by simply following the instructions on the screen. The Ugo Basile DCA Software can now be launched from the desktop icon or from the Program Files folder.

  • Page 13: General Safety Instructions

    (i.e. +18C°/+24C°, 60% relative humidity, non-condensing); Do not spray any liquid on the connectors; Keep inflammables far from the instruments. UGO BASILE DOES NOT ACCEPT ANY RESPONSIBILITY FOR PROBLEMS OR HARM CAUSED TO THINGS OR PERSONS, ARISING FROM:  incorrect electrical supply;...

  • Page 14: Getting Familiar With The Command Keys

    Page 8 47200 Instruction Manual (Rev. 1) Getting Familiar with the Command Keys After charging GSM for at least 1 hour, plug in the transducer and turn the instrument ON by pressing the ON/OFF button. ON / OFF Once the introduction is completed, the initial menu will appear as below.
  • Page 15 Page 9 47200 Instruction Manual (Rev. 1) Do not apply more than 1500gf Excessive force can permanently damage the transducer! For as long as the force is applied steadily, the Force value will indicate the pulling force in gf and the Time remaining will indicate the number of seconds left to complete the test.

  • Page 16: Routine Operation Of The Instrument

    GSM manually by pressing with a needle into the small reset hole located to the right of the display. For further assistance, please contact Ugo Basile, see paragraph 7.3-Customer Support. Routine Operation of the Instrument 4.2.1 Turning the instrument ON / OFF The Grip Strength Meter is turned ON from the OFF state, by pressing the ON/OFF button.

  • Page 17: Measure Menu

    Page 11 47200 Instruction Manual (Rev. 1) Measure Menu When Measure is selected from the Main Menu, the following window appears for a few seconds, showing:   The force range   The transducer serial number The available force ranges (see paragraph 4.4.4-Change Max Force) are...
  • Page 18 Page 12 47200 Instruction Manual (Rev. 1) The display shows that:  the measurement will be terminated automatical- ly by releasing the pressure on the transducer at the end of the test (Auto Measurement), i.e. when the animal loses grip and releases the bar.

  • Page 19: View Acquired Data

    Page 13 47200 Instruction Manual (Rev. 1) At this point, the user must choose whether to Reject Accept the results of the test. If the result is rejected, the user is given the option to repeat the previous test (Test) or finish making measurements (by pressing Exit, which brings back to the Measure Peak Force Menu).

  • Page 20: Memory Status

    Page 14 47200 Instruction Manual (Rev. 1) The current selection is indicated by the underlining, in our example 500gf. Change the setting by pressing Change, and con- firm with OK, or Exit, if don’t wish to modify the cur- rent selection.

  • Page 21: Configure Menu

    Page 15 47200 Instruction Manual (Rev. 1) Configure Menu When Configure is selected from the Main Menu, the following screen is shown: The Configure menu allows the user to adjust a number of configuration settings in GSM; these include options related to the measurement process, such as whether the...

  • Page 22: Restore Default Values

    Page 16 47200 Instruction Manual (Rev. 1) Adjust the warning noise threshold value; it may be adjusted from 100gf to 1500gf in 10gf steps with a default value of 300gf. Adjust the force value (as a percentage of the full scale range) which...

  • Page 23: Other Relevant Features Of Gsm

    Page 17 47200 Instruction Manual (Rev. 1) OTHER RELEVANT FEATURES OF GSM Battery Low Warning The voltage of the internal rechargeable battery used in GSM is monitored continuously during routine operation. Two warning levels are provided. If the battery is low but still usable, the dashed line of most menus will include Battery Low.

  • Page 24: Applied-Force Rate-Meter

    This section assumes that the DCA PC software has been installed successfully as de- scribed in paragraph 3.3.2-Installing the DCA Software. The DCA software manages the GSM, the PAM and eVF instruments by Ugo Basile. Note on the GSM PC Software...
  • Page 25 Page 19 47200 Instruction Manual (Rev. 1) Starting the DCA Software First connect the GSM device to the PC using the supplied USB cord, then run the Ugo Basile DCA (Data Collection Application) Software program from the Windows Start Menu or from the DCA icon on the desktop.
  • Page 26 Page 20 47200 Instruction Manual (Rev. 1) Starting the Experiment Now that the software is ready to work, the test-monitoring window will appear: Figure 5 “Test Monitoring”” The test-monitoring window includes the following sections: 6.3.1 Main Box As soon as the experiment is...
  • Page 27 Page 21 47200 Instruction Manual (Rev. 1) A caption on the top right of the window reminds the Transducer Max Force, as set in the instrument configuration menu. 6.3.2 Info Panel The Info Panel indicates the ac- tion in progress (in these exam-...
  • Page 28 Page 22 47200 Instruction Manual (Rev. 1) During the test, the Analysis panel is not ac- tive Once the experiment is over and the data transmitted from the device to the computer, push the button “Analyze” to open the folder where the .PAM files are saved and stored during the test.
  • Page 29 Page 23 47200 Instruction Manual (Rev. 1) By moving the black vertical line (indicated by the arrows in the above screenshot) left or right along the slope, the user will be able to select a specific moment in the test.
  • Page 30 Page 24 47200 Instruction Manual (Rev. 1) While the DCA PC software is not designed for statistical analysis, exporting the data us- ing the DCA PC software creates a user friendly file compatible with Excel. One will find this automatically generated file to be most useful, because Excel seems to be the most common spreadsheet program which allows a researcher to perform whatever analytical statistics are preferred.
  • Page 31 Page 25 47200 Instruction Manual (Rev. 1) This rate is stored in the GSM controller, so one must return to the GSM controller, toggle through the selected menus to reach the proper instructions. When the rate of application of force is changed in the internal memory of the GSM controller, it will automatically change the slope of the blue line quiiwhich is displayed in the software.
  • Page 32 47200 Instruction Manual (Rev. 1) MAINTENANCE While any service of the instrument ought to be carried out by Ugo Basile personnel or by qualified personnel authorized by UGO BASILE organization, this section of the instruc- tion manuals describes normal maintenance procedures which can be carried out at your facility.
  • Page 33 Page 27 47200 Instruction Manual (Rev. 1) ORDERING INFORMATION 47200 Meter, consisting of: GSM Grip Strength 47200-001 Electronic Unit 47200-002 Force Transducer 47200-004 Black PVC Base w/13mm Upright Trapeze (Rat) M-LM 590 Trapeze (Mouse) M-LM 588 T-shaped Bar M-LM 589 47200-325...
  • Page 34 Total weight 4.8Kg Shipping Weight 6.5Kg Packing Dimensions 46x38x27cm Warranty 47200 is covered by a 24-month warranty BIBLIOGRAPHY 10.1 Papers Mentioning UB Grip Strength Meter - Mouse R. Barone et alia: “Skeletal muscle Heat shock protein 60 increases after  ...
  • Page 35 Page 29 47200 Instruction Manual (Rev. 1) D. Lafont et alia: “A Novel Role for Receptor Like Protein Tyrosine Phos-   phatase Zeta in Modulation of Sensorimotor Responses to Noxious Stimuli: Evidences from Knockout Mice Studies” Behav. Brain Res. 201:...
  • Page 36 N o t e s _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _...
  • Page 37 N o t e s _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _...
  • Page 38 N o t e s _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _...
  • Page 39 CE CONFORMITY STATEMENT Manufacturer UGO BASILE srl Address Via G. di Vittorio, 2 – 21036 Gemonio, VA, ITALY Phone n. +39 0332 744574 Fax n. +39 0332 745488 We hereby declare that Instrument. GRIP STRENGTH METER Catalog number 47200 It is manufactured in compliance with the following European Union Directives and relevant harmonized standards ...

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